Agenda

Date and TimeTitle
Oct 2, 2020
8:00am - 8:30am (Central)
Welcome and Opening Keynote

Chairs: David R. Gandara, USA & Christian Rolfo, USA & Maria Arcila, USA   

  • Chair's Welcome   
  • Personalizing Lung Cancer Treatment – Pasi Janne, USA   
  • Live Q&A
Oct 2, 2020
8:30am - 9:40am (Central)
Understanding the Basics of Liquid Biopsy (ctDNA)

Chair: Lynette Sholl, USA

  • Preanalytics in ctDNA Handling: A Crucial Point – Umberto Malapelle, Italy
  • Technologies Update from Single to Multiple Determinations – Ignacio Wistuba, USA
  • Advantages and Disadvantages to In-house vs Outsourcing Analyses with Liquid Biopsy – David R. Gandara, USA & Maria Arcila, USA
  • Live Q&A with all Presenters Moderated by Lynette Sholl, USA
Oct 2, 2020
9:55am - 12:13pm (Central)
Clinical Application of Liquid Biopsy (ctDNA)

Chair: Natasha Leighl, Canada

  • Integrating Liquid Biopsy into Clinical Practice: Which Patients with NSCLC? – Natasha Leighl, Canada
  • Presentation of IASLC Consensus Statement Results – Christian Rolfo, USA
  • Clinical Cases in Molecular Tumor Board Debate: Case Advanced NSCLC - Adenocardinoma – Natasha Leighl, Canada; Lecia Sequist, USA; Tony Mok, Hong Kong
  • Live Q&A moderated by Natasha Leighl, Canada
  • Cross Fire Session: Liquid versus Tissue Biopsy… or Complementary – Maria Arcila, USA & Marina Garassino, Italy
  • Quantitation of Variant Allele Frequency and Variants in the Decision-Making Process: Molecular Biology Perspective and Pathology Perspective – Phil Mack, USA & Lynette Sholl, USA
  • Live Q&A Moderated by Natasha Leighl, Canada
Oct 2, 2020
12:13pm - 12:53pm (Central)
Prime Time for Blood First?

Chair: Maria Arcila, USA

  • No, Tissue is the Issue – Fred R. Hirsch, USA
  • Yes, It Is Prime Time – Rafal Dziadziuszko, Poland
  • Live Q&A Moderated by Maria Arcila, USA
Oct 2, 2020
12:53pm - 1:59pm (Central)
Liquid Biopsy and Checkpoint Immunotherapy (CPI)

Chairs: Benjamin Besse, France & Shirish Gadgeel, USA

  • Tumor Mutational Burden (TMB): Moving from Tumor Tissue to Blood – Phil Mack, USA
  • Analytical and Clinical Validation of a Blood TMB Assay – David R. Gandara, USA
  • Other Potential Predictive Biomarkers in ctDNA for CPI – Maximilian Diehn, USA
  • Live Q&A Moderated by Benjamin Besse & Shirish Gadgeel
  • Closing Remarks of the Day – Giorgio Scagliotti, Italy
Oct 3, 2020
8:00am - 8:55am (Central)
What are the Real Challenges for a Worldwide Application?

Chairs: Kazuto Nishio, Japan & Harpreet Singh, USA & Christian Rolfo, USA

  • Liquid Biopsy Regulations from FDA Perspective – Harpreet Singh, USA
  • Panel Discussion: What Are the Real Challenges for a Worldwide Application?
    • Laureen Leiman, USA
    • Nikki Martin, USA
    • Michelle Turner, USA
    • Harpreet Singh, USA
    • Chandra Belani, USA
  • Live Q&A Moderated by Christian Rolfo, USA
Oct 3, 2020
8:55am - 9:40am (Central)
Understanding Other Members of the Liquid Biopsy Family

Chair: Harpreet Singh, USA

  • Liquid Biopsy and Clonal Evolution of Lung Cancer - Collin Blakely, USA
  • Cancer Interception: A New Opportunity for Liquid Biopsy – Lecia Sequist, USA
  • Live Q&A Moderated by Harpreet Singh, USA
Oct 3, 2020
9:55am - 11:41am (Central)
Increasing Roles for Liquid Biopsy: Moving from Research to Clinical Application

Chairs: Chandra Belani, USA & Charu Aggarwal, USA

  • Detection of Early Stage Disease: Complementary or Replacement for CT Screening – Nir Peled, Israel
  • Early Detection of Recurrence after Surgery: TRACERx, Minimal Residual Disease and Adjuvant Trials – Chris Abbosh, UK
  • Liquid Biopsy for Detection of Minimal Residual Disease – Tetsuya Mitsudomi, Japan
  • Live Q&A with all Presenters Moderated by Charu Aggarwal, USA
  • Liquid Biopsy for Tumor Monitoring – Natasha Leighl, Canada
  • Liquid Biopsy for Determination of Mechanisms of Resistance – Charu Aggarwal, USA
  • ctRNA: Exploring Other Opportunities in Liquid Biopsy – Luis Raez, USA
  • Live Q&A with all Presenters Moderated by Chandra Belani, USA
Oct 3, 2020
12:40pm - 1:21pm (Central)
Liquid Biopsy in Clinical Trials

Chair: Christian Rolfo, USA

  • Integrating Liquid Biopsy in Lung Cancer Clinical Trial Design – Benjamin Besse, France
  • Update of the Ongoing Trials in Liquid Biopsy – Rafal Dziadziuszko, Poland
  • Live Q&A Moderated by Christian Rolfo, USA
Oct 3, 2020
2:00pm - 2:19pm (Central)
Closing Session

Closing Remarks:

  • Christian Rolfo, USA
  • Maria Arcila, USA
  • David R. Gandara, USA